This paper presents comparisons between two types of structural optimization methods currently available in the commercial program GENESIS. The paper describes the traditional and established topology method and discusses the implementation of the newer topometry method. The paper describes the common components of the two methods and their main differences. Details such as what element types are available for each method and what types of analysis and responses can be used for each method are presented. Examples that illustrate the use, similarities and differences of the two methods are also presented.